致癌因素是指能使人群或实验动物群体中恶性肿瘤发病率显著增加的物质或因素。可分为物理性、化学性和生物性三类。物理性致癌因素主要是放射性,约占人类肿瘤病因的5-10%。生物性致癌因素主要是致瘤性病毒,如热带性恶性淋巴瘤(Burkitt 氏瘤)及鼻咽癌,可能与E-B病毒有关。生物性致癌约占肿瘤病因的5%左右,由于遗传因素引起的肿瘤不超过5%。其余约80%的肿瘤是由于化学致癌物引起的。确定致癌因素,需要经过动物致癌实验和人群流行病学调查。
世界华人消化杂志 Key Words: MicroRNAs; Gastric cancer; Tumor suppressor genes; Carcinogenic factors [gap=464]关键词: 微小RNA; 胃癌; 抑癌基因; 致癌因素
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诱发性肿瘤模型 诱发性肿瘤模型是使用致癌因素(Carcinogens)在实验条件下诱发动物发生肿瘤的动物模型, 原理是利用外源性致癌因素引起细胞遗传特性异常而呈现出异常生长和高增殖活性,形成肿...
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So we can conclude that the mutation of HER-2 at codon 655(A→G),which leads to the Ile/Val single nucleotide polymorphism ,maybe a kind of carcinogenic agent and may influence clinical outcomes.
由此推断HER-2基因Ile655Val突变(A→G)可能是一种致癌因素,并可能影响临床结果,预示不良预后。
参考来源 - 中国人群HER·2,447,543篇论文数据,部分数据来源于NoteExpress
难道现代生活中就不存在致癌因素吗?
But aren't there elements of modern life that cause cancers?
膀胱癌最主要的致癌因素是抽烟。
The most significant risk factor associated with Bladder cancer is smoking.
它具有高效、安全、有一定营养价值、无任何致癌因素等特点。
It has many advantages, such as high efficiency, safety, good nutritive value and non-carcinogen.
For example, how cancer diagnosis has improved, what are some of the causes of cancer in the environment around us and how can we protect ourselves from it, and we'll talk about treatments for it as well.
例如癌症的诊断手段是如何进步的,我们周围环境中有哪些致癌因素,以及我们如何保护自己免受其害,我们也会讨论到癌症的治疗手段
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