异常的超变和异常的致癌基因 BCL-6 与淋巴瘤的发生具有相关性。

Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 are associated with lymphomagenesis.

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一部分原因在于，癌症的出现往往要经历数十年，因此，要想揭示其导致癌症发生率的增加，必须要对实验对象进行长时间的跟踪。

Part of the problem is that cancer can take decades to appear, so only a lengthy follow-up will expose an increase in its incidence.

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但是由于研究显示，这种疗法更易导致癌症，心血管疾病等的发生，不少女性不得不停止治疗，所以新的研究目标在于单独使用睾酮，而不再结合雌性激素的疗法。

Many women have stopped the combination therapy because of studies linking it to cancer, cardiovascular and other risks, so the new study looked at women given testosterone without estrogen.

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