我们都知道当刺激感受疼痛的神经元,其释放的化学物质称为核苷酸,特别是三磷酸腺苷(atp)。
It is already known that when pain-sensing neurons are stimulated, they release chemicals known as nucleotides, specifically adenosine triphosphate (ATP).
肌肉细胞中由腺苷衍生而来的核苷酸,细胞反应的主要能源。
A a nucleotide derived from adenosine that occurs in muscle tissue; the major source of energy for cellular reactions.
结论:吗啡影响神经细胞嘌呤核苷酸代谢,使细胞内腺苷酸及腺苷水平增高,这可能是吗啡依赖和耐受形成的机理之一。
Conclusion morphine may affect purine nucleotide metabolism of nerve cells, increase the adenylate and adenosine levels, which may be one of the mechanism of morphine dependence and tolerance.
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