...词：药剂学；脂质体制备；齐多夫定碳酸胆固醇酯；包封率；Zeta电位 [gap=1178]Key words: pharmaceutics; liposomes preparation; cholesteryl carbonate zidovudine; entrapment efficiency; Zeta potential ..
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结论脂质体制备工艺可行，药剂学性质稳定。
CONCLUSION This preparation of BLCL is practicable and the pharmaceutical characterization showed stable.
脂质体制备的难点在于改善物理稳定性和提高包封率。
Physical stability and envelope rate remains the main problems in preparation of liposomes.
以包封率为评价指标，筛选脂质体制备的最佳工艺条件。
The optimal technological conditions were acquired by the evaluation of the encapsulation efficiencies.
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