胶质细胞增生为在中枢神经系统受损处,星形胶质细胞的大量增生。星状细胞为相对较大的一种胶质细胞,具有多种功能,并会在神经元受损处堆积。脑中特定部位的胶质细胞增生及神经元的失去常被发现于各种神经退化性疾病 (neurodegenerative disorder),例如科尔萨科夫氏症候群 (Korsakoff's syndrome), 多发性硬化症, 及艾滋病痴呆综合症 (AIDS dementia complex)。
回顾性分析经手术与病理证实的13例胶质细胞增生症病人的临床资料。
Methods Clinical data of 13 patients with pathologically confirmed gliosis were analyzed retrospectively.
目的:探讨乌司他丁对新生鼠缺氧缺血性脑病脑重量及脑细胞变性、坏死、凋亡、胶质细胞增生的影响。
Objective: To study the effect of Ulinastatin on brain weight and cerebrocellular degeneration, necrosis, apoptosis and gliocyte hyperplasia of hypoxic-ischemia encephalopathy in newborn rats.
结果:毛果芸香碱惊厥持续状态模型鼠病理损伤特点为神经元坏死、细胞凋亡、凋亡蛋白表达增多,胶质细胞增生。
RESULTS: Neuron necrosis, apoptosis, increase of apoptosis protein expression and proliferation of glial cells were the characteristics of pathological injury in the pilocarpine induced se models.
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