本研究以天然甲壳素为原料,通过简单的化学、物理处理,制得一种用于人工肝的吸附解毒剂。
A new adsorptive antidote was prepared from a natural chitin raw material by simple chemical and physical treatment.
分别测定治疗剂量、中毒剂量、致死剂量组小鼠在用药一段时间后的肝肾功能,并进行组织病理学检查。
Hepatic and renal functions, and tissue biopsy were measured in rats with therapeutic, toxic and lethiferous dose treatment after a period of time.
结果染毒后小鼠脾、肝、肺、肾组织细胞DNA出现损伤,且损伤程度与染毒剂量具有一定相关性。
Results DNA of spleen, liver, lung and kidney cells was significantly damaged after exposure, and there were some correlation between exposure concentration and damage degree.
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