血清碱性磷酸酶、骨和尿中钙含量和羟脯氨酸含量变化。
Changes in serum alkaline phosphatase (AKP), calcium and hydroxyproline contents in bone and urine were all measured.
方法以L -羟脯氨酸为原料，合成一系列神经氨酸酶抑制剂，并用高通量活性筛选方法检测其对神经氨酸酶的抑制活性。
METHODS a series of pyrrolidine derivatives were synthesized from L-hydroxyproline, and the neuraminidase inhibitory activities of these compounds were tested using high throughput screening.
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