这本书描述了从绝望到高兴的心理变化过程。

The book describes a spiritual journey from despair to happiness.

《牛津词典》

她发出了绝望的叫声。

She uttered a cry of despair.

《牛津词典》

他们常常陷入孤独、屈辱和绝望的深渊。

They frequently plumb the depths of loneliness, humiliation, and despair.

《柯林斯英汉双解大词典》

A desperate honesty that throbs through his confession does not absolve him from sins of diabolical cunning. He is abnormal.

他的忏悔被绝望的虔诚悸动着,但这也不能为他那恶魔的狡诈赎罪，他是变态。

耶鲁公开课 - 1945年后的美国小说课程节选

This is the modern city, not as a scene of fragmentation or despair, but rather a place of ascent and aspiration.

这是一座现代化的城市，并不是破碎或绝望的场景，而是一座在上升的渴望之城。

耶鲁公开课 - 现代诗歌课程节选

But at the same time the Market Revolution is going to bring a certain sense of anxiety, even dread, even despair.

同时市场革命将,带来某种焦虑,甚至是可怕的和绝望的

耶鲁公开课 - 美国内战与重建课程节选