例如，某些蛋白质的过量会导致细胞异常增殖并癌变；胰岛素蛋白质的缺乏会导致糖尿病。

For example, an excess of certain proteins can cause cells to proliferate abnormally and become cancerous; a lack of the protein insulin results in diabetes.

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在与 NF1 相关的肿瘤中神经纤维蛋白表达的丧失与 RAS 活性升高和细胞增殖增加有关。

Loss of neurofibromin expression in NF1-associated tumors is associated with elevated RAS activity and increased cell proliferation.

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相反，miR-17~92是通过帮助缺乏肿瘤抑制Rb蛋白的细胞增殖而发挥作用的。

Rather, miR-17~92 acts to help cells that lack the tumor-suppressing Rb protein to proliferate.

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