近年来的研究发现，许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
研究了环六亚甲基双乙酰胺对人成骨肉瘤MG-63细胞的增殖和相关基因表达的影响。
In this paper, we studied the effects of HMBA on the proliferation and expression of genes in human osteosarcoma MG-63 cells.
结论PASG基因作为上游调控基因，通过改变基因组甲基化水平调控下游一系列细胞增殖分化相关基因表达。
Conclusions AS an upstream regulator, PASG can regulate expression of a series of cell proliferation, differentiation relevant downstream genes through changing methylation levels of genomic DNA.
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