刘春华 头孢曲松钠对谷氨酸诱导皮质神经细胞损伤的影响 关键词】 头孢曲松钠;谷氨酸;细胞内钙;谷氨酸转运体 [gap=1776]Key words:Ceftriaxone;glutamate;intracellular calcium;glutamate transporters
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细胞内钙离子 Intracellular calcium
细胞内钙流 calcium fluxes
细胞内钙荧光强度 FI
细胞内钙离子浓度 intracellular calcium concentration ; intracellular Ca concentration
细胞内钙库 intracellular ca store
细胞内游离钙离子 intracellular free calcium ; IFCA
及脑细胞内游离钙离子 intracellular free calcium ; IFCA
细胞内游离钙 cytosolic free calcium ; Intracellular free calcium
Laser scanning confocal microscope was used to measure intracellular calcium fluorescence pixel values of hippocampal neurons.
激光共聚焦显微镜检测锥体细胞内钙离子荧光像素值。
参考来源 - 纳洛酮对血管性痴呆大鼠空间学习记忆损害的预防作用及其神经机制研究The results showed that:1. After treatment with 3mM KCN for 15min,Ca~(2+)_i in hippocampal neuronswas significantly increased 6.27±0.05-fold compared with pre-anoxia level(P<0.05) and 73.3%±12.1% of the cells died (P<0.05).2.
结果显示:1、给予原代培养的海马神经元KCN(3mM)处理15min后,细胞内钙离子浓度(Ca~(2+)i)显著升高至缺氧前6.27±0.05倍(p<0.05),73.3%±12.1%细胞死亡(P<0.05)。
参考来源 - 细胞缺氧损伤中TRPM7介导的凋亡机制及NGF对TRPM7调节机制研究The opening of the L-type calcium channel will be useful to influx pathways of Ca~(2+) and rise the intracellular Ca~(2+) concentration.
而L-型钙通道的开放可以促使钙离子向细胞内流动,使细胞内钙离子浓度升高。
参考来源 - 巴戟素改善脑缺血再灌注损伤作用的实验研究The ryanodine-induced Ca2+i increase was markedly inhibited by anandamide (100nM) in Ca2+-free Tyrode’s solution.
在无钙台式液中,anandamide(100nM)可抑制由ryanodine所致的细胞内钙浓度的升高。
参考来源 - 内源性大麻素物质anandamide对大鼠的心脏保护作用及其机制The results suggested that PI-PLC involved in changing the process of intracellular calcium homeostasis, and the effect of verapamil was closely associated with the phosphoinositide signaling pathway in the tumor cells.
提示PI-PLC可能参与肿瘤细胞内钙恒稳的变化过程,异搏定的作用可能与磷脂酰肌醇信号传导系统相关。
参考来源 - 异搏定对小鼠肝癌腹水瘤细胞系PI·2,447,543篇论文数据,部分数据来源于NoteExpress
快速心房起搏可导致细胞内钙离子超载。
两个钙通道拮抗剂均能显著减少两组的细胞内钙。
The two calcium channel blockers can significantly decrease the intracellular calcium in both groups.
雌激素能拮抗兴奋性氨基酸毒性,稳定细胞内钙离子溶度。
Estrogen can resist the excitability amino acid toxicity and stable the solubility of calcium ion in cells.
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