...蛋白装配成子代病毒释放至细胞,另有小部分重新回到肝细胞核内转变为cccDNA,这种方式称之为细胞内通路(intracellular pathway)。由此,eccDNA在宿主肝细胞核内积聚,形成cccDNA池(cccDNA p001)。
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新的研究发现了一种通过操纵宿主细胞内的一种常见信号通路来破坏早期宿主免疫反应并提高致病性的以前未知的酶反应机制。
New research identifies a previously unknown enzymatic mechanism that subverts the early host immune response and promotes pathogenicity by manipulating a common signaling pathway in host cells.
这项研究说明了EGFR–SGLT1通路通过维持细胞内的葡萄糖水平,阻止自噬性细胞死亡,从而为肿瘤细胞提供了生存优势。
This study reveals that EGFR–SGLT1 may confer a survival advantage to cancer cells by maintaining a basal level of intracellular glucose and preventing autophagy.
已经提出了几个假说来连接物理力和细胞内信号转导通路但是许多情况中机械转导的机制还不清楚。
Several hypotheses have been advanced that link physical forces to intracellular signalling pathways, but in many cases the molecular mechanisms of mechanotransduction remain elusive.
So, this pathway might not be the only one that's being activated inside the cell at any given time.
因此,任一时刻细胞内,激活的信号通路不只是一条
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