胶原敷料(Collagen Dressings) 组织工程皮肤替代物(Tissue Engineered Skin Substitutes) 施冰芳，周玲丽，郑漫艳.银离子抗菌敷料治疗PICC置管穿刺点感染的疗效.
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真皮替代物是组织工程皮肤的重要组成部分。
Dermal substitute is an important component of the tissue engineering skin.
组织工程化皮肤研究一直是当前研究的热点，目前尚无特别有效的皮肤替代物应用于临床。
Tissue engineering skin is a hot spot recently, but up to now there are no effective skin substitute which can be extensively applied in clinic.
结论：以胎儿皮肤为细胞来源、牛i型胶原为支架的全层组织工程皮肤，是一种良好的生物活性皮肤替代物，可用来修复全层皮肤缺损。
Conclusion: Human skin with full thickness can be tissue engineered with foetus back skin as the sources of epithelial cells and fibroblasts, and bovine I type collagen as carrier.
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