红细胞发生的研究主要依赖于MEL细胞系和分离到的少量的小鼠成红细胞。
Most studies of erythropoiesis have been performed either with the virally transformed MEL cells or with the scarce erythroblasts within unhomogeneous cell populations.
成熟红细胞的寿命是有限的,它们的产生和凋亡必须保持精确平衡,否则会发生疾病。
Mature RBC have a finite life span; their production and destruction must be carefully balanced, or disease ensues.
当发生血管内溶血性贫血,更多红细胞在血液循环(血红蛋白血症)被破坏以至于超出肝球蛋白质的结合能力。
In intravascular hemolytic anemia, more RBC are destroyed in the circulation (hemoglobinemia) than can be bound to haptoglobin.
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