与之相反,L -甲硫氨酸增加了甲基化水平,从而减弱了正常老鼠中糖皮质激素受体基因的表达,导致了恐惧、焦虑和对压力的强烈反应。
By contrast, L-methionine increased the level of methylation and thus reduced the expression of the gene in animals with loving mothers, and led to fear, anxiety and a heightened response to stress.
结果:研究表明50岁及以上的女性服用TZD、糖皮质激素,髓袢利尿剂和自报活动受限的其骨折风险增加具有统计学意义。
RESULTS: We found statistically significant increased odds of exposure to TZDs, glucocorticoids, loop diuretics, and self-reported limited mobility for women 50 yr of age and older with fractures.
对不吸入糖皮质激素的患者来说,规律使用沙美特罗与规律使用沙丁胺醇相比,其致死性及非致死性严重不良事件的发生率并无显著增加。
Compared with regular salbutamol, regular salmeterol was not associated with a significant increase in fatal or nonfatal serious adverse events in patients not taking inhaled corticosteroids.
应用推荐