目的:对天然五环三萜进行结构修饰,寻找新型糖原代谢调控药物。
Aim: to search for novel modulators of glycogen metabolism through structural modifications of natural pentacyclic triterpenes.
PAF在许多生物学过程中,如前炎症细胞的信号传导和活化、改变血管通透性、刺激糖原代谢以及其它方面起着重要的作用。
PAF has been implicated as a mediator of physiological processes such as signaling and activation of proinflammatory cells, alteration of vascular permeability, and stimulation of glycogen metabolism.
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