类脂是广泛存在于生物组织中的天然大分子有机化合物,这些化合物的共同特点是都具有很长的碳链,但结构中其它部分的差异却相当大。它们均可溶于乙醚、氯仿、石油醚、苯等非极性溶剂,不溶于水。常见的类脂化合物有蜡、油脂、磷脂、萜类、甾族化合物及一些维生素等。
Liposome is a kind of ultra-fine form globular carrier preparation which encapsulates the drug in the thin film formed by lipid bilayer.
脂质体是将药物包封于类脂双分子层形成的薄膜中间所制成的超微型球状载体制剂。
参考来源 - 氟康唑脂质体及脂质体凝胶的研制The innate immune system is the first line of the defensive mechanisms that protect hosts from invading microbial pathogens. Host cells express various pattern recognition receptors(PRRs) that sense diverse pathogen-associated molecular patterns(PAMPs),ranging from lipids, lipoproteins,proteins and nucleic acids.
天然免疫是机体防御微生物病原体入侵第一道防线,机体细胞通过表达不同的模式识别受体(Pattern recognition receptors,PRRs),来识别包括类脂,脂蛋白,蛋白和核酸在内的各种病原相关分子模式(Pathogen-associated molecular patterns,PAMPs),激活机体细胞内信号通路,诱导炎症细胞因子和趋化因子及干扰素的表达,上调细胞表面MHCⅡ类分子和共刺激分子从而参与适应性免疫应答。
参考来源 - 猪TLR7和MyD88基因克隆,组织表达谱分析及MyD88酵母表达的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
它们活跃地分解脂肪化合物和类脂。
动物脂肪与植物油都是简单类脂体。
而类脂多肽将在提高药物输送系统效率方面起到重要作用。
Here these designer lipid-like peptides may play a key role in improving effective drug delivery systems.
Steroids are small molecules - much smaller than proteins - smaller molecules that tend to be hydrophobic or lipid soluble.
类固醇是小分子物质,比蛋白质小得多,这类小分子是非水溶性的,或者说是脂溶性的
So most of the lipids, which make up cell membranes in your body are of this category of phospholipids.
大部分脂类,那些在你体内构成细胞膜的脂类,都属于磷脂类
Fatty acid chains are fat molecules, they behave, if you have a lot of them in solution like oil.
脂肪酸链就是脂肪分子,它们看上去好像,如果你见过富含脂类的溶液,比如油
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