我们提出了肺结核分支杆菌细胞色素P 450 CYP121与三氮唑类药物氟康唑的复合物的晶体结构，揭示了唑类与亚铁血红素新的结合模式。
We present here the crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121 in complex with the triazole drug fluconazole, revealing a new azole heme ligation mode.
某些罕见的遗传性疾病会造成患者对分支杆菌属极其易感，这一类细菌中的一些成员就是结核病和麻风病的病原体。
Some rare genetic diseases can make patients susceptible to infections with Mycobacterium species, the bacteria that amongst other diseases, cause tuberculosis and leprosy.
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