方法应用肠道细菌毒力和侵袭力检测、宋内菌大质粒DNA图谱分析和猴体口服耐受试验对S7株、S7R株进行安全性和稳定性分析。
Methods Making use of enterobacterial virulence and invasive test, DNA profile analysis and challenge test of rhesus monkey to determine the safety and stability of S7 and S7R.
目的构建以融合蛋白形式在大肠杆菌中高效表达心钠素的重组质粒，稳定高效地获得基因工程产品心钠素。
Objective To construct recombinant plasmid with human atrial natriuretic peptide (ANP) gene in fusion form for stable and high level expression of genetic engineering product ANP in E. coli system.
对重组菌中重组质粒的稳定性进行研究，结果表明该质粒在宿主菌中具有良好的分离稳定性，而结构稳定性较差。
The plasmid stability studies showed that recombinant plasmid has excellent segregational stability but the structural stability was not good in the host cell.
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