吗啡通过作用于神经突触来缓解疼痛，但它同时也兴奋了胶质细胞，可能也加剧了该药的副作用，如嗜睡，耐受，疼痛加剧和成瘾。
Morphine deadens pain by acting at nerve synapses, but it also activates glial cells, possibly worsening the drug's side effects, such as drowsiness, tolerance, worsening of pain, and addiction.
结论：吗啡影响神经细胞嘌呤核苷酸代谢，使细胞内腺苷酸及腺苷水平增高，这可能是吗啡依赖和耐受形成的机理之一。
Conclusion morphine may affect purine nucleotide metabolism of nerve cells, increase the adenylate and adenosine levels, which may be one of the mechanism of morphine dependence and tolerance.
结论胸腺内注射异基因MHC抗原可诱导大鼠对异体坐骨神经移植的特异性免疫耐受。
Conclusion Intrathymus injection of allogene MHC antigen might induce specific immune tolerance to sciatic nerve allografts in mice.
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