被动吸烟可使鼠胎神经管上皮细胞过度凋亡,实验组均较对照组有明显增多的细胞凋亡。
Smoking can cause excessive apoptosis in neural tube of experimental group, more apoptosis cells were observed in neural epithelium compared with the control group.
结论被动吸烟可以促使神经管上皮细胞的过度凋亡,可能是导致神经管畸形发生的重要原因之一。
Conclusion Passive smoking can cause excessive apoptosis in neural epithelium, which may be one of the important ways by which the deformation of neural tube will occur.
方法采用核固红结晶紫染色方法,原位末端标记法及形态计量方法定量分析了被动吸烟致金黄地鼠神经管上皮细胞凋亡的变化。
Methods By using the nuclear fast red-crystal violet staining method and situ TUNEL technology, the quantitative changes of apoptosis in neural epithelium in gold hamster were analyzed.
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