目的利用组织工程技术体外重建角膜上皮组织，为眼表重建提供良好的移植材料及方法。

Objective To reconstruct corneal epithelium in vitro by tissue engineering technique and provide effective method and materials for clinical transplantation.

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干眼泪腺和眼表上皮细胞的凋亡异常增加，而局部组织中的淋巴细胞的凋亡却被抑制。

Apoptosis in lacrimal gland and ocular surface epithelium increase abnormally, but in local lymphocytic cell is inhibitted in dry eye .

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结论糖尿病导致的泪腺、角膜、结膜等眼组织破坏是糖尿病性眼表病变的病理基础。

Conclusions Diabetes can cause lacrimal gland, corneal and conjunctival tissue damage, which is the pathological foundation of the diabetic ocular surface disease.

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