讨 论 白血病多药耐药(multidrug resistence,MDR)是指白血病细胞对结构、功能和杀伤机制不同的不同种药物产生耐受,一旦细胞对某种药物产生耐受,即可以对多...
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结论FFJZ可能成为治疗白血病多药耐药安全有效的逆转药物。
Conclusion FFJZ may become a safe and effective multidrug resistance-reversing agent with low toxicity in leukemia chemotherapy.
该技术为白血病多药耐药的基础和临床研究开辟了新思路,也为新的分子诊断和分子治疗提供可能。
It is a new way for the study of multidrug resistance of leukemia. RNAi may be a new research tool of molecular diagnosis and molecular therapy on leukemia in the future.
目的通过检测儿童急性白血病多药耐药基因及细胞凋亡调控基因表达水平的改变,分析不同类型白血病的主要耐药机制。
Objective To study the drug resistance in different types of acute leukemia in children, the expression of multidrug resistance gene and apoptosis-related genes were analyzed.
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