近年来的研究发现,许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
肿瘤的发生是原癌基因激活、抑癌基因失活以及凋亡相关基因失调等诸多因素综合作用的结果。
The development of tumor results from complex action among multiple factors such as oncogene activation, anti-oncogene inactivation, disturbance of apoptosis related gene and so on.
因此,探讨不同类型肿瘤相关癌基因和抑癌基因是认识肿瘤发生分子机理、开展基因诊断和基因治疗的基本前提。
Therefore, the detection of oncogenes and TSGs in different tumors is the basic prerequisite to understand the mechanism of tumorigenesis and to conduct gene diagnosis and gene therapy.
应用推荐