通过比较接种组和对照组人群，经过一个疫苗预防疾病的流行周期（一般为一年），观察登记两组疫苗目标疾病的发病情况，比较组的发病率，计算疫苗保护率，进行流行病学效果评价。
增强动物抗病防御和免疫应答能力，提高疫苗保护率是当前防治传染性疾病最可靠的简便途径。
A strategy to enhance immune responses to conventional vaccines and DNA vaccines is very important in further development of the vaccine to control animal infectious diseases.
这项由1.6万名志愿者参加的试验结果表明，在接受注射人群中，疫苗的保护率为31%。
The results of the trial, which involved more than 16,000 volunteers, suggested that the vaccine was 31% effective at preventing infection among those who were inoculated.
方法以不同剂量霍乱疫苗免疫小鼠，用间接elisa方法检测小鼠全血的抗菌、抗毒抗体滴度，小鼠毒菌攻击法计算保护率。
Methods The mice were immunized by different doses of cholera vaccine. Titer of antiserum against cholera strain and toxin were tested by indirect enzyme-linked immunosorbent assay (ELISA).
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