目的考察注射用盐酸头孢替安与甲硝唑注射液配伍的稳定性。
Objective To evaluate the compatible stability of cefotiam hydrochloride for injection with metronidazole injection.
目的研究头孢噻肟与甲硝唑注射液的配伍稳定性,为临床合理用药提供科学依据。
OBJECTIVE to determine the stability of cefotaxime in metronidazole injection and to offer a scientific basis for rational use of drug in clinical practice.
方法:采用超滤法结合高效液相色谱法测出游离药物浓度,比较未加和加入甲硝唑后头孢噻肟钠的蛋白结合率。
Method: Ultrafiltration and HPLC were employed to measure the conc. of free drug. The difference in protein-binding between cefotaxime alone and together with metronidazole was examined.
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