甲基赖氨酸,化学结构简式为H2NCH2CH2CH2CH2CH(NH2)COOH,能够提高智力、促进生长、增强体质 增进食欲、改善营养不良状况。
IL-6与DN的肾小管损害_南京肾病就医网 化蛋白终末产物(advanced glycation end products,AGEs)产生增多,尤其是羧甲基赖氨酸(carboxymethyllysine,CML)修饰蛋白,随之发生对氧化还原作用敏感的转录因子NF-κB的激活,NF-κB激活引起细胞因子IL-6的
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目前,研究最广泛、常作为AGEs 代表的是戊糖素(Pentosidine)和羧甲基赖氨酸(Carboxymethyllysine,CML),戊 糖素的含量只占总AGEs的1%,但普遍存在于人体蛋白质半衰期长的组织中, 山东大学硕I‘学位论...
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羧甲基赖氨酸 CML ; carboxy methyl lysine
泛甲基赖氨酸抗体 pan methyl Lysine ; Anti-pan methyl Lysine
小鼠羟甲基赖氨酸 mouse CML
二甲基赖氨酸水解酶 DDAH ; di methylarginine di methy-laminohydrolase
羧甲基赖氨酸复合物 carboxymethyl-lysine adducts ; CML
三甲基赖氨酸 trimethyl lysine
三甲基赖氨酸抗体 Trimethyl Lysine Antibody
尤其是羧甲基赖氨酸 carboxy methyl lysine ; CML ; crboxymethyllysine
泛甲基赖氨酸 Anti-pan methyl Lysine
过去甲基化的结构研究被阻碍的原因是因为很难制备组蛋白特定部位赖氨酸甲基化的均一样品。
Past structural studies of methylation were hindered by the extreme difficulty of constructing homogeneous samples of histones bearing methyl groups attached to specific lysine residues.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰,在基因的表观遗传转录调控中起着关键的作用。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
组蛋白H3第27位赖氨酸的甲基化与同源盒基因沉默、X染色体失活、基因印记等基因沉默现象有关;
The methylation of histone H3-K27 was proved to be linked to several silencing phenomena including homeotic-gene silencing, X inactivation and genomic imprinting.
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