这些疾病合在一起使人致盲、致残、变丑、失去能力，或者在其它情况下估计损及12亿人的生活。

Together, these diseases blind, maim, disfigure, disable, and otherwise impair the lives of an estimated 1.2 billion people.

youdao

她咕哝道，把抽屉猛地一推关上，”我将终生劳碌，只能偶尔得到一点乐趣，逐渐变老变丑，变得尖酸刻薄，就因为我穷，不能像其他女孩子一样享受生活。

I shall have to toil and moil all my days, with only little bits of fun now and then, and get old and ugly and sour, because I'm poor and can't enjoy my life as other girls do.

youdao

可如果你生活中就是有人告诉你，你胖/丑/做人失败呢？

But what if there is someone in your life actually telling you that you are fat or ugly or a failure?

youdao