热重于湿是中医药理论的一种病证,症见身热稽留,汗出不退,渴不引饮或喜热饮,胸闷泛恶,四肢倦怠,身重头蒙,神情呆钝,小便浑浊,大便溏泄,脉象濡缓,舌苔白腻等。治疗以苦寒消热为主,兼以化湿。
目的:根据中医理论和动物模型的研制原则,模拟临床病因,建立温病湿热证湿重于热动物模型。
Objective: Established the animal model of dampness-heat syndrome more damp with less heat of epidemic febrile disease by simulating clinical pathogeny according to basic theories of TCM.
结果该模型从症状体征、生化、药物反证等方面,均证明近似于温病湿热证湿重于热的临床表现。
Result: it was suggested that the symptoms, body signs, biochemistry and medical disproof of the animal model are similar with clinic situation of SFD symptom of WEOHE.
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