生物机体在热应激(或其他应激)状态下所表现的以基因表达变化为特征的防御适应反应称为热休克反应(heat shock response,HSR)。而在热应激(或其他应激)时新合成或者合成增多的一组蛋白质称为热休克蛋白(heat shock protein,HSP)。热休克反应也具有应激反应的基本特征,即非特异性和防御适应性。
另一方面,人们认识到,机体尚有对抗脑出血所带来的种种损害的自身保护机制,热休克反应(heat shock response)即是其中之一,以HO-1和HSP70两种热休克蛋白为代表。
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Heat shock protein is a group of protein and its name originrd from heat shock response.
热休克蛋白是一组蛋白,它的命名来源于热休克反应。
参考来源 - 精索静脉曲张患者精浆HSP70的变化及临床意义HSPs are prevalently popular in the whole biosphere . When organisms are under irritable condition such as heat shock reaction(HSR),infected by pathogens, or induced by amino acid , growth factor and heavy metal etc, HSPs will be markedly increased ?
其普遍存在于从细菌到高等真核生物的整个生物界,在正常生长条件下,各种细胞处于应激状态时,如热休克反应(HSR)或环境温度改变、病原体感染和组织损伤,被氨基酸类似物、生长因子、重金属高子等多种因素可诱导其在体内明显增高。
参考来源 - 清热复方对热休克大鼠HSP70基因表达调控的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:探讨热休克反应对急性运动大鼠心肌自由基代谢的影响。
This study is designed to test the effect of heat shock response on rat heart after an acute bout exercise.
探讨热休克反应(HSR)对内毒素(LPS)所致MAPK信号通路的影响。
ObjectiveTo explore the effect of heat shock response(HSR) on the LPS-stimulated MAPK pathways.
目的:探讨热休克反应(HSR)对热暴露大鼠心血管系统的保护作用及机制。
AIM: To study protective effects and mechanism of heat shock response (HSR) on cardiovascular system in rats after heat exposure.
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