虽然这些病人得到了包括化疗在内的系统化治疗，肝癌通常被认为是化疗抵抗性肿瘤。

Although these patients receive systemic treatment including chemotherapy, HCC is generally recognized as a chemo-resistant tumor.

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众所周知，血清胰岛素基值升高提示生长激素治疗可能对治疗前有明显胰岛素抵抗性的患者不利。

Of note, baseline serum insulin level was high, suggesting that growth hormone therapy might be problematic in patients with significant pretreatment insulin resistance.

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