转氨酶水平轻微升高可能反映了甲氨蝶呤对肝脏的早期毒性作用，尽管也可能是全身感染引起的非特异性反应。
The slightly elevated levels of aminotransferases may reflect an early toxic effect of methotrexate on the liver, although a nonspecific response to a systemic infection is also possible.
主要反映在给药方案、重复用药、溶媒不当、药理拮抗、配伍禁忌、毒性相加及用法错误等方面。
Irrational USES reflected in dosage project, repeated medication, dissolvant mismatch, pharmacologic antagonism, chemical incompatibility and toxicity addition.
结论病毒性肝炎患者血清细胞因子的高低，可在一定程度上反映肝细胞损害的程度，也提示上述细胞因子参与了乙型病毒性肝炎的发病过程。
Conclusion the level or expression of abovementioned cytokines reflected liver damage to some degree, and suggested that they involve in the pathogenetic process of hepatitis b.
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