当HCA抑制柠檬酸裂解酶，脂肪生成过程停止。

When HCA inhibits citrate lyase, the fat-making process is halted.

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顺乌头酸酶2 (ACO2)在三羧酸循环第二步骤中催化从柠檬酸经顺乌头酸生成异柠檬酸的异构化(1,2)。

Aconitase 2 (ACO2) catalyzes the conversion of citrate to isocitrate via cis-aconitate in the second step of the tricarboxylic acid (TCA) cycle (1, 2).

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异柠檬酸脱氢酶催化异柠檬酸氧化脱羧生成2 -氧戊二酸盐。

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.

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