...经轴突不同程度的再生及使脱 髓鞘的神经纤维形成周围类型的髓鞘,然而二者在与中枢神经 系统中 星型胶质细胞 ( astrocyte cells )的相互作用上表现出不同 的特性。
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型星形胶质细胞 type 1 astrocytes ; type-2 astrocyte ; T1AS ; T2AS
纤维型星形胶质细胞瘤 fibrillary astrocytoma
肥胖型星形胶质细胞瘤 gemistocytic astrocytoma
型星形胶质细胞祖细胞 O2A
原浆型星形胶质细胞 Flat astrocyte
星型胶质细胞同样可以释放多种信号分子来介导细胞间的通讯。
Astrocytes can also release many signal molecules that mediate intercellular communication.
选择性地裂解星型胶质细胞的溶酶体,发现ATP释放和钙波传播都消失了。
Selective intracellular lysis of lysosomes abolished both ATP release and Ca2+ wave propagation among astrocytes.
总之,星型胶质细胞的溶酶体可以通过调节性胞吐对生理和病理条件下的细胞间信号传递产生重要意义。
Together, these findings indicate that regulated lysosome release from astrocytes contribute to intercellular signaling under physiological as well as pathological conditions.
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