微生物挑战性试验是目前评价防腐剂效果的最为广泛和经典的检测方法。
The microbial challenge test, a classic method of evaluating preservation effect of cosmetics preservative is widely used in cosmetics industry.
相应地，开发过程中应进行检测条件下的微生物挑战性试验(尽可能模拟病人使用情况)并写入本部分的文件。
Where relevant, microbial challenge testing under testing conditions that, as far as possible, simulate patient use should be performed during development and documented in this section.
巴基斯坦的一个城市卡拉奇也正施行这个试验，那里的情况可以用用“富有挑战性”来描述。
Conditions in Karachi, the Pakistani city in which the trial is being conducted, could politely be described as "challenging".
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