是非折叠蛋白应答途径 unfolded protein response ; UPR
According to the“folding pathway theory”, the formation of intermediate is a key step in protein folding to reduce the searching scope for protein refolding.
“折叠途径”学说认为,在蛋白质折叠途径中必然有中间体的产生,这样才能减少蛋白质折叠所搜索的空间范围,解决“Levinthal佯谬”。
参考来源 - HAb18G/CD147胞外片段蛋白质折叠复性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
尿素浓度梯度电泳实验结果显示，存在两条不同的折叠途径。
The experimental results of urea gradient electrophoresis show that there are two different refolding processes.
本文绘出了AILP的主要氧化折叠和还原解折叠途径草图。
A schematic flow chart of major oxidative folding and reductive unfolding pathway of AILP was proposed.
这一方法可能是解决植物肌动蛋白及其他在包涵体中表达蛋白难以正确折叠和大量纯化的有效途径之一。
This may be a good method for obtaining soluble and abundant plant actin isoforms and other proteins which could not fold exactly and exist in inclusion body by prokaryotic expression.
应用推荐