抗原突变 antigenic mutation 又称抗原性漂移(antigenic drift),是指小变异引起流感的中小规模流行,一般认为抗原性漂移使得甲型流感病毒1一3年出现一次新变种.抗原性转变指大的抗原变异,变异结果产生新的不同亚型,常引起世界性大流行。 指与细菌抗原性有关的突变。如荚膜、菌体抗原、鞭毛抗原(H抗原)等的突变。
在南非追踪研究最近被感染了因突变而减毒的艾滋病毒而且无上述优势人类白细胞抗原的21名妇女。
The South African study tracked 21 women without the beneficial form of HLA who were recently infected with the weakened strain of HIV.
抗原,CD 59;糖尿病;突变;cho细胞;转染;抗补体活性。
Antigens, CD59; Mutation; CHO cells; Transfection; Anticomplement activity.
目的:对炭疽毒素保护性抗原(PA)的不同结构域进行了缺失突变,以期找到免疫原性降低而功能变化不大的PA蛋白突变体。
Objective:To find protective antigen(PA) defective mutants of anthrax toxin with the same function as PA but with low immunogenicity, different domains of PA were mutated.
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