The S protein of TGEV has four major antigenic sites, which can induce immune protecting effects as same as the whole S protein does.
而位于S蛋白近N端A、B、C、D四个主要抗原位点片段诱导产生的免疫保护作用,几乎相当于整个S蛋白产生的诱导效应。
参考来源 - 猪传染性胃肠炎病毒S基因抗原位点区的表达及其优化·2,447,543篇论文数据,部分数据来源于NoteExpress
分析它的主要功能位点表明它具有319位的糖基化位点和完整的抗原位点。
Sequence analysis result indicated GP had a glycosylation site at position 319 and whole antigenic sites.
HA1的氨基酸位点变异主要位于5个已知的抗原位点及其附近,同时其它位点也有改变。
The animo acid changes of HA1 mostly located at the antigenic sites or aside of them, but also may occur at the other sites simultaneously.
So, now you have a single molecule, very large molecule, with not just two binding sites but with ten binding sites.
所以如果你体内有一个细胞,一个体积很大的细胞,细胞表面不只有两个抗原结合位点,而有十个抗原结合位点
The advantage of this is that now you have four binding sites for antigen instead of just two.
这样的好处是一个抗体上,有四个抗原结合位点而不仅仅是两个
So, these are better at binding to antigen because they have more binding sites on them.
连接抗体是对付抗原的有效方法,因为抗体表面将会有更多的抗原结合位点
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