结果:MAPK反义寡核苷酸可明显抑制细胞活力、蛋白质含量、集落形成和DNA合成,其抑制率分别为52。6%、50。5%、54。9%和47。5%,与对照组比较差异有显著性(P<0。01)。
Results The cell viability, protein content, colony formation and DNA synthesis were significantly inhibited by MAPK ASO, the inhibitory rate was 52.6% , 50.5% , 54.9% and 47.5% respectively(P< 0.01).
不同浓度的LMW NTS对肿瘤细胞线粒体琥珀酸脱氢酶活力的影响不同,低浓度时表现为促进作用,而高浓度时表现为轻度抑制作用。
Concentration of LMW NTS had effect on mitochondrial succinodehydrogenase activity of tumor cell, lower concentration showed a promotion action, higher concentration showed a slight inhibition action.
目的:研究外源性C2神经酰胺对大鼠脑胶质瘤细胞C6活力的抑制作用以及早期凋亡诱导作用。
AIM: to investigate the effects of exogenous cell-permeable C2-ceramide on viability and early apoptosis induction in rat glioma ce ll C6.
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