结果:端粒酶反义寡聚脱氧核苷酸能诱导人胃癌细胞凋亡,抑制端粒酶活性。
Telomerase activity were detected by TRAPELISA. Results: Telomerase antisense oligodeoxynucleotides acted as a specific growth inhibitor to gastric cancer cell line.
结果:两种药物均具有抗qgy细胞增殖、阻滞细胞周期、诱导凋亡及抑制端粒酶活性的作用。
Results: These two drugs could inhibit the proliferation of QGY cells, block the cell cycle, induce its apoptosis and inhibit the activity of telomerase.
结果:ICA可明显抑制端粒酶活性,对白血病细胞均有较明显的诱导分化和抑制增殖作用,且与A TRA合用可产生明显的协同效应。
Results: ICA could inhibit the telomerase activity and induce the differentiation and restrain the proliferation of HL-60 cells. The effect was promoted by ATRA.
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