骨形态发生蛋白(BMP)是一类具有高效成骨活性的蛋白质,因其能够异位诱导间充质细胞分化为软骨和骨细胞而形成新骨,在临床骨缺损修复中具有良好的应用前景。
Bone morphogenetic protein (BMP) has good potential in treatment for bone defects as it can induce mesenchymal cells to differentiate into cartilage cells and bone cells so to form new bone.
目的从骨髓细胞分化角度研究年龄相关的成骨和破骨细胞分化的机理,探讨老年性骨质疏松症的发生机理。
Objective To discuss the mechanism of age-related the osteoblast and osteoclast differentiation from marrow cells and discuss the mechanism of aged bone loosing disease.
目的制备脱细胞松质骨作为骨形态发生蛋白2 (BMP - 2)载体,观察其异位成骨状况。
Objective to prepare acellular cancellous bone as carrier for bone morphogenetic protein 2 (BMP-2), and observe the ectopic osteogenesis.
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