a great loss ; a major loss ; an enormous loss
是一个很大的损失 be a great loss for
造成很大的经济损失 Caused great economic losses
这一事件给它带来了很大的损失。
It is suffering a great deal from the incident.
youdao
府上一定觉得这是一个很大的损失吧。
They must be a great loss to your family.
什么人死了也不怕，什么人死了就有很大的损失？
There is no need to fear for the death of anyone. Whose death would be a great loss?
应用推荐
模块上移
模块下移
不移动