未经治疗的痛风会使皮肤下沉积尿酸结石从而形成结节，成为结节瘤。
Advanced gout. Untreated gout may cause deposit of urate crystals to form under the skin in nodules called tophi (TOE-fi).
病理学上硅肺的肺损伤主要表现为小叶中心及支气管血管周围结缔组织的结节形成。
Pathologically, the pulmonary lesions seen in patients with silicosis are centrilobular, peribronchiolar nodules consisting of layers of laminated connective tissue.
结果从兔颅骨分离的细胞碱性磷酸酶染色阳性，在长期培养中能够形成钙化结节。
Results The cells from rabbit calvaria were positive to ALP staining and could form calcium node in vitro.
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