既然引起食欲的许多原因还有待发现，就很难发明一种药物来抑制食欲。
It's hard to create a drug to suppress appetite when there could be many unknown factors involved in this instinct.
但是，长时间的高应激水平会导致皮质醇水平长期升高，这可能引起食欲增加，体重上升。
Over time, high stress levels lead to chronically elevated cortisol levels that can cause increased appetite and weight gain.
因此我认为该研究最重要的作用是证实了尼古丁还能通过其它通路引起食欲下降。
So I think the most important contribution of this paper is to prove that there is another whole pathway that nicotine is working through.
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