目的：探讨胎盘异铁蛋白对小鼠胚胎生长发育的影响。

Objective: To assess the effect of placental isoferritin in vitro on mouse embryo development.

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结论血浆胎盘异铁蛋白水平的降低与胎儿生长迟缓和妊高征的发生有密切关系，血管内皮细胞损伤可能是其作用机制之一。

Conclusion The decrease of plasma PLF levels at earlier third trimester was associated with IUGR and pre-eclampsia, and the endothelial cell damage may be one of its mechanisms.

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