结论:心疾宁胶囊可通过抑制钾通道,延长动作电位时程,保护缺血心肌而抗心律失常。
It is revealed that "Xinjining Capsule" can fight arrhythmia by inhibiting K channel, prolonging action period and protecting ischemia.
目的:研究自发性高血压大鼠(SHR)左心室肌细胞动作电位时程延长的膜离子流基础。
Objective: To study the membrane ionic basis of action potential prolongation of hypertrophied left ventricular myocytes in spontaneously hypertensive rats (SHR ).
结果:心衰康煎液可以明显延长刺激引起动作电位的潜伏期及明显缩短动作电位时程。
Results: Xinshuaikang decoction could prolong the latent period of AP induced by electrical stimulation and shorten the APD Jignificantly.
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