提出采用模型变换方法，减小系统模型的不确定性，从而减小鲁棒设计的保守性。
Model transformation method are induced to avoid conservative robust design by decreasing the model uncertainties .
采用小系统概率动力学模型对实验数据进行拟合，便得到了逆反应速率和反应亲和性参数。
Reverse kinetic rate and binding affinity constants were predicted by comparing the measured data with a small system probabilistic model.
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