镜下见，肝外胆道闭锁导致肝脏大量黄绿色胆栓、假胆管增生(见于下面的中央)、广泛纤维化。

Microscopically, extrahepatic biliary atresia leads to this appearance in the liver, with numerous brown-green bile plugs, bile duct proliferation (seen at lower center), and extensive fibrosis.

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Perlmutter博士在一篇声明中称，“这些AT Z聚集体在肝细胞中堆积，最终导致肝脏瘢痕形成、纤维化，为肿瘤的发生创造条件。”

"These aggregates of ATZ accumulate in the liver cells and eventually lead to scarring, or fibrosis, of the organ and set the stage for tumor development," Perlmutter said in a statement.

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