它是一门枯燥无味、孤独凄凉、确实很令人绝望、痛苦不已的；通常我们称之为，忧郁的科学。

No, it is "a dreary, desolate, and indeed quite abject and distressing one; what we might call, by way of eminence, the dismal science."

youdao

可耻的，而且经常受伤的麦蒂向记者忏悔，“我是一个不能向比我强大的人屈服的傻瓜，我一定会在孤独凄凉中老去。”

I am simply someone who is unable to genuflect before those who have more ability than myself. And for this, I will die a lonely and pathetic death.

youdao

无论如何，这本书凄凉而精彩，对那些孤独被遗忘的人们所做的描述，凄美感人，难以忘怀。

Either way, this is a sad and wonderful book, an enduringly moving and beautiful depiction of the lonely and forgotten.

youdao

Is it true that when we die we all die having this feeling of loneliness, or perhaps feeling of alienation?

确实我们死的时候感到格外孤独凄凉，或者是感觉非常生疏？

耶鲁公开课 - 死亡课程节选