Tobian及其同事注意到，早期的研究显示包皮环切术能减少男性HPV的流行及发生率，同时观察结果提示它对女性也可能有有益的影响。

Earlier studies had shown that the procedure reduces both prevalence and incidence in men, and observations had suggested it might have a beneficial effect in women, Tobian and colleagues noted.

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